Phenotypes Associated with This Genotype

Genotype
MGI:5430592

• Allelic Composition: Tg(Pklr-Myc)73Ak/0
• Genetic Background: B6.Cg-Tg(Pklr-Myc)73Ak

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased hepatocellular carcinoma incidence ( J:184496 )

immune system

decreased NK T cell number ( J:184496 )

• the proportion of invariant NKT cells in the liver is lower than in controls

hematopoietic system

decreased NK T cell number ( J:184496 )

• the proportion of invariant NKT cells in the liver is lower than in controls

liver/biliary system

increased hepatocellular carcinoma incidence ( J:184496 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hepatocellular carcinoma		DOID:684	OMIM:114550	J:184496