Phenotypes Associated with This Genotype

Genotype
MGI:5431537

• Allelic Composition: Gm572^b2b1167Clo/Gm572^b2b1167Clo
• Genetic Background: C57BL/6J-Gm572^b2b1167Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1167-020-LB shows heterotaxy with right lung isomerism

cardiovascular system

double outlet right ventricle ( J:175213 )

dextrocardia ( J:175213 )

atrioventricular septal defect ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

right pulmonary isomerism ( J:175213 )

situs inversus totalis ( J:175213 )

hematopoietic system

spleen hypoplasia ( J:175213 )

immune system

spleen hypoplasia ( J:175213 )

liver/biliary system

abnormal liver morphology ( J:175213 )

• mid-line liver

respiratory system

immotile respiratory cilia ( J:175213 )

right pulmonary isomerism ( J:175213 )

cellular

immotile respiratory cilia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Kartagener syndrome		DOID:0050144		J:175213
primary ciliary dyskinesia		DOID:9562	OMIM:PS244400	J:175213
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213