Phenotypes Associated with This Genotype

Genotype
MGI:5431549

• Allelic Composition: Daw1^b2b1584Clo/Daw1^b2b1584Clo
• Genetic Background: C57BL/6J-Daw1^b2b1584Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1584-004-LC displays heterotaxy indicated by dextrocardia, right aortic arch, dual IVC and levogastria

cardiovascular system

abnormal aortic arch morphology ( J:175213 )

right aortic arch ( J:175213 )

abnormal inferior vena cava morphology ( J:175213 )

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

abnormal atrioventricular valve morphology ( J:175213 )

dextrocardia ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

abdominal situs ambiguus ( J:175213 )

left pulmonary isomerism ( J:175213 )

respiratory system

left pulmonary isomerism ( J:175213 )

liver/biliary system

abnormal liver morphology ( J:175213 )

hematopoietic system

absent spleen ( J:175213 )

immune system

absent spleen ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Kartagener syndrome		DOID:0050144		J:175213
primary ciliary dyskinesia		DOID:9562	OMIM:PS244400	J:175213
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213