Phenotypes Associated with This Genotype

Genotype
MGI:5432177

• Allelic Composition: Gt(ROSA)26Sor^{tm49(HTT)Arte}/Gt(ROSA)26Sor⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:243843 )

• mice live for a median period of 289 days

behavior/neurological

impaired coordination ( J:243843 )

• mice exhibit impaired rotarod performance at 6 months of age

decreased vertical activity ( J:243843 )

• mice show reduced rearing at 4 and 5 months of age

decreased locomotor activity ( J:243843 )

• mice show reduced number of floor plan moves in the open field at 5 months of age

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Huntington's disease		DOID:12858	OMIM:143100	J:243843