Phenotypes Associated with This Genotype

Genotype
MGI:5432229

• Allelic Composition: Grm1^{Tg(p18A4.B)1352Szc}/0
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal melanocyte proliferation ( J:32786 )

• melanocytosis

hyperpigmentation ( J:32786 , J:83183 )

• on the ears, snout and rectal/perianal region (J:32786)

• in the pinnae of the ear, perianal region, eyelid, snout, trunk, legs and occasionally distant organs (J:83183)

neoplasm

increased cutaneous melanoma incidence ( J:32786 , J:83183 )

• in the ear, snout, fungoid rectum/perianus and pubis (J:32786)

• multiple melanomas primarily in the pinnae of the ear, perianal region, eyelid, snout, trunk and legs (J:83183)

integument

increased cutaneous melanoma incidence ( J:32786 , J:83183 )

• in the ear, snout, fungoid rectum/perianus and pubis (J:32786)

• multiple melanomas primarily in the pinnae of the ear, perianal region, eyelid, snout, trunk and legs (J:83183)

cellular

abnormal melanocyte proliferation ( J:32786 )

• melanocytosis

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
skin melanoma		DOID:8923	OMIM:608035 OMIM:612263	J:83183