Phenotypes Associated with This Genotype

Genotype
MGI:5435559

• Allelic Composition: Porcn^tm1Vdv/Porcn⁺
• Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Digit, vertebral, kidney, and reproductive system abnormalities in Porcn^tm1Vdv/Y and Porcn^tm1Vdv/Porcn⁺ chimeras

reproductive system

abnormal uterine horn morphology ( J:186934 )

♀ • rudimentary

renal/urinary system

hydronephrosis ( J:186934 )

♀

skeleton

fused phalanges ( J:186934 )

♀ • absent, fused, and shortened digits on 1 to all 4 of the extremities

abnormal caudal vertebrae morphology ( J:186934 )

♀

limbs/digits/tail

fused phalanges ( J:186934 )

♀ • absent, fused, and shortened digits on 1 to all 4 of the extremities

brachydactyly ( J:186934 )

♀ • absent, fused, and shortened digits on 1 to all 4 of the extremities

oligodactyly ( J:186934 )

♀ • absent, fused, and shortened digits on 1 to all 4 of the extremities

abnormal caudal vertebrae morphology ( J:186934 )

♀

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
focal dermal hypoplasia		DOID:2120	OMIM:305600	J:186934