Phenotypes Associated with This Genotype

Genotype
MGI:5435560

• Allelic Composition: Porcn^tm1Vdv/Y
• Genetic Background: chimera involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Digit, vertebral, kidney, and reproductive system abnormalities in Porcn^tm1Vdv/Y and Porcn^tm1Vdv/Porcn⁺ chimeras

reproductive system

small testis ( J:186934 )

♂

renal/urinary system

hydronephrosis ( J:186934 )

♂

skeleton

fused phalanges ( J:186934 )

♂ • absent, fused, and shortened digits on 1 to all 4 of the extremities

abnormal caudal vertebrae morphology ( J:186934 )

♂

limbs/digits/tail

fused phalanges ( J:186934 )

♂ • absent, fused, and shortened digits on 1 to all 4 of the extremities

brachydactyly ( J:186934 )

♂ • absent, fused, and shortened digits on 1 to all 4 of the extremities

oligodactyly ( J:186934 )

♂ • absent, fused, and shortened digits on 1 to all 4 of the extremities

abnormal caudal vertebrae morphology ( J:186934 )

♂

endocrine/exocrine glands

small testis ( J:186934 )

♂

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
focal dermal hypoplasia		DOID:2120	OMIM:305600	J:186934