Phenotypes Associated with This Genotype

Genotype
MGI:5435675

• Allelic Composition: Fktn^tm1Kcam/Fktn^tm1Kcam; Tg(Ckmm-cre)5Khn/?
• Genetic Background: involves: 129S/SvEv * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

dystrophic muscle ( J:187144 )

• signs of dystrophic disease at 12 weeks of age

• central nucleation in muscle fibers

• variable fiber size

• hypercontracted fibers

homeostasis/metabolism

increased circulating creatine kinase level ( J:187144 )

• elevated serum creatine kinase at 12 weeks of age

behavior/neurological

weakness ( J:187144 )

• reduced running times on a treadmill

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Fukuyama congenital muscular dystrophy		DOID:0050559	OMIM:253800	J:187144