Phenotypes for Lrp1 MGI:5437118 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lrp1^b2b1554Clo/Lrp1^b2b1554Clo
Genetic Background	C57BL/6J-Lrp1^b2b1554Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp1^b2b1554Clo mutation (1 available); any Lrp1 mutation (211 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 1554-004-1 (E14.5) exhibits gastroschisis with liver and gut outside the abdominal cavity (celoschisis)

cardiovascular system

atrioventricular septal defect ( J:175213 )

growth/size/body

abnormal body wall morphology ( J:175213 )

• body wall closure defects

herniated abdominal wall ( J:175213 )

omphalocele ( J:175213 )

muscle

diaphragmatic hernia ( J:175213 )

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
congenital diaphragmatic hernia	DOID:3827	OMIM:142340 OMIM:222400 OMIM:610187	J:175213
gastroschisis	DOID:11044	OMIM:230750	J:175213
omphalocele	DOID:0060327	OMIM:164750	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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