Phenotypes for Lrp1 MGI:5437118 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Lrp1^b2b1554Clo/Lrp1^b2b1554Clo
Genetic Background	C57BL/6J-Lrp1^b2b1554Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp1^b2b1554Clo mutation (1 available); any Lrp1 mutation (211 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 1554-004-1 (E14.5) exhibits gastroschisis with liver and gut outside the abdominal cavity (celoschisis)

cardiovascular system

atrioventricular septal defect ( J:175213 )

growth/size/body

abnormal body wall morphology ( J:175213 )

• body wall closure defects

herniated abdominal wall ( J:175213 )

omphalocele ( J:175213 )

muscle

diaphragmatic hernia ( J:175213 )

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
congenital diaphragmatic hernia	DOID:3827	OMIM:142340 OMIM:222400 OMIM:610187	J:175213
gastroschisis	DOID:11044	OMIM:230750	J:175213
omphalocele	DOID:0060327	OMIM:164750	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24