About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5438218
cn3
Allelic
Composition		 Ctnnb1tm1Mmt/Ctnnb1+
Trp53tm1Brn/Trp53+
Tg(Fabp7-cre,-lacZ)3Gtm/0
Genetic
Background		 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ctnnb1tm1Mmt mutation (0 available); any Ctnnb1 mutation (49 available)
Tg(Fabp7-cre,-lacZ)3Gtm mutation (1 available)
Trp53tm1Brn mutation (18 available); any Trp53 mutation (240 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased medulloblastoma incidence ( J:186709 )
• by 11 months, 4% of mice develop WNT-subgroup medulloblastomas

nervous system
increased medulloblastoma incidence ( J:186709 )
• by 11 months, 4% of mice develop WNT-subgroup medulloblastomas

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory