Phenotypes Associated with This Genotype

Genotype
MGI:5441373

• Allelic Composition: Tg(Rho*G90D*A337V)202Sie/0
• Genetic Background: involves: C57BL/6 * DBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:188632 )

N • unlike other models of nightblindness, mice do not exhibit loss of rods

abnormal rod electrophysiology ( J:188632 )

• reduced dark-adapted b-wave threshold without rod degeneration

• rod sensitivity is depressed and required higher flash intensity

• for half maximal responses, the time to pear is faster than for wild-type mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
congenital stationary night blindness autosomal dominant 1		DOID:0110862	OMIM:610445	J:188632