About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5441555
Allelic
Composition		 Krastm4Tyj/Kras+
Trp53tm1Lejo/Trp53tm1Lejo
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm4Tyj mutation (9 available); any Kras mutation (84 available)
Trp53tm1Lejo mutation (0 available); any Trp53 mutation (235 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased lung non-small cell carcinoma incidence ( J:187012 )
• following infection with adenovirus-FLPe/IRES/Cre (Ad-FIC)
increased lung adenocarcinoma incidence ( J:187012 )
• following infection with Ad-FIC

respiratory system
increased lung non-small cell carcinoma incidence ( J:187012 )
• following infection with adenovirus-FLPe/IRES/Cre (Ad-FIC)
increased lung adenocarcinoma incidence ( J:187012 )
• following infection with Ad-FIC

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
lung cancer DOID:1324 OMIM:211980
OMIM:608935
OMIM:612571
OMIM:612593
OMIM:614210
 J:187012

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/03/2024
MGI 6.24 		The Jackson Laboratory