Phenotypes Associated with This Genotype

Genotype
MGI:5442143

• Allelic Composition: Dnaaf3^b2b1739Clo/Dnaaf3^b2b1739Clo
• Genetic Background: C57BL/6J-Dnaaf3^b2b1739Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

EFIC summary

cardiovascular system

abnormal aortic arch morphology ( J:175213 )

right aortic arch ( J:175213 )

abnormal vein morphology ( J:175213 )

abnormal inferior vena cava morphology ( J:175213 )

dual inferior vena cava ( J:175213 )

dextrocardia ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

abdominal situs ambiguus ( J:175213 )

abdominal situs inversus ( J:175213 )

left pulmonary isomerism ( J:175213 )

situs inversus totalis ( J:175213 )

respiratory system

immotile respiratory cilia ( J:175213 )

left pulmonary isomerism ( J:175213 )

cellular

immotile respiratory cilia ( J:175213 )

skeleton

abnormal vertebral column morphology ( J:175213 )

• malaligned sternal vertebra

liver/biliary system

abnormal liver morphology ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Kartagener syndrome		DOID:0050144		J:175213
primary ciliary dyskinesia 2		DOID:0110626	OMIM:606763	J:175213
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213