Phenotypes for Pkd1 MGI:5445215 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Pkd1^b2b1585Clo/Pkd1^b2b1585Clo
Genetic Background	C57BL/6J-Pkd1^b2b1585Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1^b2b1585Clo mutation (1 available); any Pkd1 mutation (154 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 1585-003-NA displays highly cystic kidneys

cardiovascular system

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

craniofacial

micrognathia ( J:175213 )

renal/urinary system

polycystic kidney ( J:175213 )

skeleton

micrognathia ( J:175213 )

growth/size/body

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

polycystic kidney ( J:175213 )

muscle

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
hypertrophic cardiomyopathy	DOID:11984		J:175213
polycystic kidney disease 1	DOID:0110858	OMIM:173900	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24