Phenotypes for Pkd1 MGI:5445215 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Pkd1^b2b1585Clo/Pkd1^b2b1585Clo
Genetic Background	C57BL/6J-Pkd1^b2b1585Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1^b2b1585Clo mutation (1 available); any Pkd1 mutation (154 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 1585-003-NA displays highly cystic kidneys

cardiovascular system

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

craniofacial

micrognathia ( J:175213 )

renal/urinary system

polycystic kidney ( J:175213 )

skeleton

micrognathia ( J:175213 )

growth/size/body

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

polycystic kidney ( J:175213 )

muscle

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

Mouse Models of Human Disease	DO ID	OMIM ID(s)	Ref(s)
hypertrophic cardiomyopathy	DOID:11984		J:175213
polycystic kidney disease 1	DOID:0110858	OMIM:173900	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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