Phenotypes Associated with This Genotype

Genotype
MGI:5445936

• Allelic Composition: Scn5a^{tm1(SCN5A)Rdn}/Scn5a^{tm3(SCN5A*)Rdn}
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

dilated heart left ventricle ( J:189389 )

• intermediate at 12 weeks

dilated cardiomyopathy ( J:189389 )

decreased cardiac muscle contractility ( J:189389 )

• intermediate at 12 weeks

decreased heart rate ( J:189389 )

• intermediate at 3 weeks

prolonged P wave ( J:189389 )

• intermediate at 3 and 12 weeks

prolonged QRS complex duration ( J:189389 )

• intermediate at 3 weeks

muscle

dilated cardiomyopathy ( J:189389 )

decreased cardiac muscle contractility ( J:189389 )

• intermediate at 12 weeks

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
dilated cardiomyopathy 1E		DOID:0110433	OMIM:601154	J:189389