Phenotypes Associated with This Genotype

Genotype
MGI:5445972

• Allelic Composition: b2b1709Clo/b2b1709Clo
• Genetic Background: C57BL/6J-b2b1709Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Necropsy of 1709-003-MLA shows hypoplastic LV.

cardiovascular system

aortic arch hypoplasia ( J:175213 )

vascular ring ( J:175213 )

coronary fistula ( J:175213 )

overriding aortic valve ( J:175213 )

small mitral valve ( J:175213 )

• small mitral valve

mitral valve hypoplasia ( J:175213 )

• hypoplastic mitral valve

ventricular septal defect ( J:175213 )

decreased heart left ventricle size ( J:242757 )

heart left ventricle hypoplasia ( J:175213 )

craniofacial

abnormal craniofacial morphology ( J:175213 )

nervous system

holoprosencephaly ( J:175213 )

vision/eye

cyclopia ( J:175213 )

anophthalmia ( J:175213 )

growth/size/body

microcephaly ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hypoplastic left heart syndrome		DOID:9955	OMIM:241550 OMIM:614435	J:175213