Phenotypes Associated with This Genotype

Genotype
MGI:5445973

• Allelic Composition: Ccdc39^b2b1735Clo/Ccdc39^b2b1735Clo
• Genetic Background: C57BL/6J-Ccdc39^b2b1735Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1735-003-1 (E 15.5) displays dextrocardia and malpositioning of the atria and outflow tract with left pulmonary isomerism

cardiovascular system

vascular ring ( J:175213 )

double outlet right ventricle ( J:175213 )

atrial septal defect ( J:175213 )

dextrocardia ( J:175213 )

growth/size/body

heterotaxia ( J:175213 )

abdominal situs ambiguus ( J:175213 )

abdominal situs inversus ( J:175213 )

left pulmonary isomerism ( J:175213 )

situs inversus totalis ( J:175213 )

respiratory system

immotile respiratory cilia ( J:175213 )

left pulmonary isomerism ( J:175213 )

cellular

immotile respiratory cilia ( J:175213 )

craniofacial

micrognathia ( J:175213 )

skeleton

micrognathia ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Kartagener syndrome		DOID:0050144		J:175213
primary ciliary dyskinesia 14		DOID:0110598	OMIM:613807	J:175213
visceral heterotaxy		DOID:0050545	OMIM:306955 OMIM:605376 OMIM:606325 OMIM:613751 OMIM:614779 OMIM:PS306955	J:175213