Phenotypes Associated with This Genotype

Genotype
MGI:5446380

• Allelic Composition: b2b1430Clo/b2b1430Clo
• Genetic Background: C57BL/6J-b2b1430Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1430-014-NC has a right aortic arch and hypoplastic aorta.

cardiovascular system

right aortic arch ( J:175213 )

double outlet right ventricle ( J:175213 )

d-loop transposition of the great arteries ( J:175213 )

decreased heart left ventricle size ( J:175213 )

• little or no lumen in the small, muscle bound left ventricle

heart left ventricle hypoplasia ( J:175213 )

craniofacial

cleft palate ( J:175213 )

short snout ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

renal/urinary system

kidney cyst ( J:175213 )

hydronephrosis ( J:175213 )

renal hypoplasia ( J:175213 )

absent kidney ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

short snout ( J:175213 )

kidney cyst ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hypoplastic left heart syndrome		DOID:9955	OMIM:241550 OMIM:614435	J:175213