neoplasm
• mice develop tumors within 20 months
|
• in some mice
|
• in some mice
|
• lymphomas often spread to the spleen, kidney and liver
|
• mice begin to develop diffuse large B-cell lymphoma starting at 15 months of age, with variation in formation from 15 to 20 months
(J:245679)
• a circulating microRNA signature predicts the development of lymphoma
(J:245679)
|
• in some mice
|
digestive/alimentary system
• in some mice
|
cellular
• in mouse embryonic fibroblasts under a 3T9 protocol
• in the spleen of premalignant aged mice
|
liver/biliary system
• in some mice
|
hematopoietic system
immune system
growth/size/body
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
diffuse large B-cell lymphoma | DOID:0050745 | J:245679 |