Phenotypes Associated with This Genotype

Genotype
MGI:5460885

• Allelic Composition: Hbb-b1^Rbc13/Hbb-b1^Rbc13
• Genetic Background: involves: BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:190446 )

• die by E18.5

integument

pallor ( J:190446 )

• progressive pallor starting at E16.5

liver/biliary system

abnormal liver morphology ( J:190446 )

• fetal livers contain poorly hemoglobinized erythroblasts with inclusions

liver hypoplasia ( J:190446 )

• fewer fetal liver cells

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
beta thalassemia		DOID:12241	OMIM:613985	J:190446