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Phenotypes Associated with This Genotype
Genotype
MGI:5466574
cx3
Allelic
Composition		 Hormad2tm1Kura/Hormad2tm1Kura
Spo11tm1Mjn/Spo11tm1Mjn
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hormad2tm1Kura mutation (1 available); any Hormad2 mutation (33 available)
Spo11tm1Mjn mutation (2 available); any Spo11 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:192634 )
N
• unlike Spo11tm1Mjn homozygotes, mice exhibit normal ovarian weights and oocyte numbers
abnormal female meiosis ( J:192634 )
• pseudo-sex body formation in oocytes is impaired
abnormal testis morphology ( J:192634 )
• as in single homozytoes

endocrine/exocrine glands
abnormal testis morphology ( J:192634 )
• as in single homozytoes

cellular
abnormal female meiosis ( J:192634 )
• pseudo-sex body formation in oocytes is impaired

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory