Phenotypes Associated with This Genotype

Genotype
MGI:5476432

• Allelic Composition: Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo
• Genetic Background: C57BL/6J-Plxnd1^b2b1863Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1863-002-4 (E16.5) has a hypoplastic transverse arch and malaligned great arteries

cardiovascular system

right aortic arch ( J:175213 )

dual inferior vena cava ( J:175213 )

persistent truncus arteriosus type ii ( J:175213 )

• truncus arteriosus type IIa

double outlet right ventricle ( J:175213 )

atrioventricular septal defect ( J:175213 )

craniofacial

cleft palate ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

renal/urinary system

absent kidney ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
DiGeorge syndrome		DOID:11198	OMIM:188400	J:175213