Phenotypes Associated with This Genotype

Genotype
MGI:5476434

hm1

• Allelic Composition: b2b1879Clo/b2b1879Clo
• Genetic Background: C57BL/6J-b2b1879Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 1879-002-NA shows abnormal placement of the outflow with malformed pulmonary trunk and is diagnosed with DORV by EFIC imaging

cardiovascular system

abnormal myocardium compact layer morphology ( J:175213 )

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

persistent truncus arteriosus ( J:175213 )

persistent truncus arteriosus type i ( J:175213 )

double outlet right ventricle ( J:175213 )

muscular ventricular septal defect ( J:175213 )

craniofacial

micrognathia ( J:175213 )

cleft palate ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

skeleton

micrognathia ( J:175213 )

renal/urinary system

absent kidney ( J:175213 )

growth/size/body

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

cleft palate ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )