Phenotypes for b2b1929Clo MGI:5476437 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	b2b1929Clo/b2b1929Clo
Genetic Background	C57BL/6J-b2b1929Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
b2b1929Clo mutation (1 available); any b2b1929Clo mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 1929-003-1 (E14.5) exhibits malrotated heart with abnormal OFT alignment and abnormal placement of atrial appendages, with left atrium markedly enlarged

cardiovascular system

dual inferior vena cava ( J:175213 )

double outlet right ventricle ( J:175213 )

atrioventricular septal defect ( J:175213 )

pulmonary valve atresia ( J:175213 )

growth/size/body

situs inversus totalis ( J:175213 )

respiratory system

abnormal respiratory motile cilium physiology ( J:175213 )

• immotile/dyskinetic

absent lungs ( J:175213 )

cellular

abnormal respiratory motile cilium physiology ( J:175213 )

• immotile/dyskinetic

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
primary ciliary dyskinesia		DOID:9562	OMIM:PS244400	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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