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Phenotypes Associated with This Genotype
Genotype
MGI:5486680
Allelic
Composition		 Tg(Camk2a-DISC1)37Asaw/Tg(Camk2a-DISC1)37Asaw
Genetic
Background		 C57BL/6-Tg(Camk2a-DISC1)37Asaw
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased dopamine level ( J:194985 )
• baseline extracellular dopamine is decreased in the ventral striatum

nervous system
abnormal striatum morphology ( J:194985 )
• dopamine transporter is increased in the striatum increase in the levels of dopamine D2 receptor in the striatum

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
schizophrenia DOID:5419 OMIM:181500
 J:194985

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory