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Phenotypes Associated with This Genotype
Genotype
MGI:5490775
cn1
Allelic
Composition
Cptm1Hrs/Cptm1Hrs
Hephtm1.1Jdun/Hephtm1.1Jdun
Tg(BEST1-cre)1Jdun/0
Tg(Rho-cre)#Yzl/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cptm1Hrs mutation (1 available); any Cp mutation (76 available)
Hephtm1.1Jdun mutation (0 available); any Heph mutation (11 available)
Tg(BEST1-cre)1Jdun mutation (1 available)
Tg(Rho-cre)#Yzl mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• iron levels in retinal pigment epithelium cells are not increased beyond levels in Cptm1Hrs/Cptm1Hrs Hephtm1.1Itl/ Hephtm1.1Itl Tg(BEST1-cre)1Jdun mice
• bipolar cells exhibit an increase in L-ferritin levels


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory