Phenotypes Associated with This Genotype

Genotype
MGI:5492070

cn4

• Allelic Composition: Elovl4^tm3Kzh/Elovl4^tm3Kzh; Tg(Rho-cre)#Yzl/?
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:194246 )

N • no rod loss

N • no marked abnormalities in the number of photoreceptor cell rows or outer nuclear layer thickness

N • no ultrastructural abnormalities

N • normal ERG and normal visual performance up to 6.5 months

abnormal retina rod cell morphology ( J:194246 )

• statistically significant decrease in very long chain polyunsaturated fatty acid content of rods

homeostasis/metabolism

decreased unsaturated fatty acids level ( J:194246 )

• statistically significant decrease in very long chain polyunsaturated fatty acid content of rods

nervous system

abnormal retina rod cell morphology ( J:194246 )

• statistically significant decrease in very long chain polyunsaturated fatty acid content of rods