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Phenotypes Associated with This Genotype
Genotype
MGI:5499286
cx6
Allelic
Composition		 Sirt2tm1.2Auw/Sirt2tm1.2Auw
Tg(SOD1*G93A)1Gur/0
Genetic
Background		 involves: 129 * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sirt2tm1.2Auw mutation (0 available); any Sirt2 mutation (27 available)
Tg(SOD1*G93A)1Gur mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:194977 )
• as in Tg(SOD1*G93A)1Gur mice

nervous system
abnormal innervation pattern to muscle ( J:194977 )
• reduced innervation as in Tg(SOD1*G93A)1Gur mice
decreased neuron number ( J:194977 )
• as in Tg(SOD1*G93A)1Gur mice
abnormal action potential ( J:194977 )
• reduced compound action potential amplitudes as in Tg(SOD1*G93A)1Gur mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory