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Phenotypes Associated with This Genotype
Genotype
MGI:5499740
Allelic
Composition
Myh9tm7.1Rsad/Myh9tm7.1Rsad
Genetic
Background
involves: BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myh9tm7.1Rsad mutation (0 available); any Myh9 mutation (219 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• with neutrophil inclusions in the bone marrow
• in the bone marrow and spleen
• contain Myh9 aggregates
• increased diameter
• macrothrombocytopenia

homeostasis/metabolism

immune system
• contain Myh9 aggregates

renal/urinary system
• focal segmental glomerulosclerosis and focal global glomerulosclerosis beginning at 4 months

vision/eye
• bilateral in some mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
MYH-9 related disease DOID:0060651 OMIM:155100
J:175367


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory