Phenotypes Associated with This Genotype

Genotype
MGI:5501103

• Allelic Composition: Rpe65^tm1Tmr/Rpe65^tm1Tmr
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

short photoreceptor outer segment ( J:136882 )

• rod outer segments decrease in length

retina photoreceptor degeneration ( J:136882 )

retina cone cell degeneration ( J:136882 )

• rapid degeneration of cone photoreceptors, with M/L-opsin almost completely absent at P28 and S-opsin totally absent at P42

retina rod cell degeneration ( J:136882 )

• slow rod photoreceptor degeneration

vision/eye

short photoreceptor outer segment ( J:136882 )

• rod outer segments decrease in length

retina photoreceptor degeneration ( J:136882 )

retina cone cell degeneration ( J:136882 )

• rapid degeneration of cone photoreceptors, with M/L-opsin almost completely absent at P28 and S-opsin totally absent at P42

retina rod cell degeneration ( J:136882 )

• slow rod photoreceptor degeneration

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Leber congenital amaurosis 2		DOID:0110016	OMIM:204100	J:136882