Phenotypes Associated with This Genotype

Genotype
MGI:5515769

hm1

• Allelic Composition: Car5a^tm1Sly/Car5a^tm1Sly
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:196135 )

• both males and females are smaller than controls

mortality/aging

mortality/aging ( J:196135 )

N • normal survival

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:196135 )

N • blood glucose levels are like controls both when fed and while fasting

abnormal homeostasis ( J:196135 )

• elevated levels of alpha-ketoglutarate, fumarate, malate, acetoacetate, subaric acid, and sebacic acid

increased circulating ammonia level ( J:196135 )

• significantly elevated