Phenotypes Associated with This Genotype

Genotype
MGI:5516012

• Allelic Composition: b2b2153Clo/b2b2153Clo
• Genetic Background: C57BL/6J-b2b2153Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2153-001-NB exhibits DORV and hypertrophy

cardiovascular system

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

double outlet right ventricle, ventricular defect committed to aorta ( J:175213 )

ventricular septal defect ( J:175213 )

craniofacial

micrognathia ( J:175213 )

cleft palate ( J:175213 )

lowered ear position ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

skeleton

micrognathia ( J:175213 )

vision/eye

abnormal eye morphology ( J:175213 )

enophthalmos ( J:175213 )

microphthalmia ( J:175213 )

anophthalmia ( J:175213 )

hearing/vestibular/ear

lowered ear position ( J:175213 )

limbs/digits/tail

curly tail ( J:175213 )

growth/size/body

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

cleft palate ( J:175213 )

lowered ear position ( J:175213 )

muscle

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cardiomyopathy		DOID:0050700		J:175213