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Phenotypes Associated with This Genotype
Genotype
MGI:5521335
cx42
Allelic
Composition
Dmdmdx/Y
Foxn1nu/Foxn1nu
Genetic
Background
involves: C57BL/10ScSn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dmdmdx mutation (31 available); any Dmd mutation (156 available)
Foxn1nu mutation (43 available); any Foxn1 mutation (106 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• elevated hydroxyproline levels in the heart, tibialis anterior and soleus when normalized to wet weight but not on a per muscle basis in mice at 3 weeks of age but not at 24 weeks of age
• unlike in mice homozygous for Dmdmdx alone, necrosis has not started at 3 weeks of age
• in the tibialis anterior at 3 weeks of age
• in the soleus muscles at 3 weeks of age


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory