Phenotypes Associated with This Genotype

Genotype
MGI:5521588

hm2

• Allelic Composition: Tgm2^tm1.1Rmgr/Tgm2^tm1.1Rmgr
• Genetic Background: B6.129S1-Tgm2^tm1.1Rmgr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

increased body weight ( J:200838 )

• Background Sensitivity: mice on a a congenic C57BL/6 background exhibit increased body weight when fed a high fat diet unlike mice on a congenic 129S1/Sv background

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:200838 )

N • whether fed standard chow or a high fat diet, mice exhibit normal glucose tolerance, insulin sensitivity and glucose stimulated insulin secretion