Phenotypes Associated with This Genotype

Genotype
MGI:5523900

• Allelic Composition: Cntn1^usl/Cntn1^usl
• Genetic Background: B6.MRL-Cntn1^usl/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal motor coordination/balance ( J:203032 )

• homozygotes splay their hind legs, stagger from side-to-side, and a few may lean their head to the side or circle slowly

ataxia ( J:203032 )

abnormal limb posture ( J:203032 )

• hind limbs can be splayed

mortality/aging

prenatal lethality, incomplete penetrance ( J:203032 )

• lower than expected Mendelian ratio of homozygotes from heterozgyous intercross indicates embryonic or perinatal lethality

preweaning lethality, complete penetrance ( J:203032 )

• all homozygotes die by 3 weeks of age

growth/size/body

decreased body size ( J:203032 )

• runted body size and lack of vitality

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Compton-North congenital myopathy		DOID:0080101	OMIM:612540	J:222308