Phenotypes Associated with This Genotype

Genotype
MGI:5523973

• Allelic Composition: Pax3^Sp-1Wli/Pax3^Sp-1Wli
• Genetic Background: involves: C57BL/6J * CBA/CaJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:196572 )

• some resorbed embryos are identified around E14.5

prenatal lethality, complete penetrance ( J:196572 )

• no live offspring are produced

embryo

abnormal neural tube morphology ( J:196572 )

• at E12.5

spina bifida ( J:196572 )

• at E12.5

nervous system

abnormal neural tube morphology ( J:196572 )

• at E12.5

spina bifida ( J:196572 )

• at E12.5

exencephaly ( J:196572 )

• at E12.5

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
neural tube defect		DOID:0080074	OMIM:301410 OMIM:601634	J:196572