Phenotypes Associated with This Genotype

Genotype
MGI:5526091

• Allelic Composition: Tg(ACTB-KRAS*G12V,-luc)#Lche/0
• Genetic Background: involves: C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased lung tumor incidence ( J:199528 )

• mice treated with an adenovirus expressing Cre recombinase (AdCre) develop lung tumors after 6-8 weeks

increased lung adenoma incidence ( J:199528 )

• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas

increased lung adenocarcinoma incidence ( J:199528 )

• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas

respiratory system

increased lung tumor incidence ( J:199528 )

• mice treated with an adenovirus expressing Cre recombinase (AdCre) develop lung tumors after 6-8 weeks

increased lung adenoma incidence ( J:199528 )

• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas

increased lung adenocarcinoma incidence ( J:199528 )

• tumors in AdCre treated mice are multiple papillary adenomas and invasive papillary adenocarcinomas

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
lung cancer		DOID:1324	OMIM:211980 OMIM:608935 OMIM:612571 OMIM:612593 OMIM:614210	J:199528