Phenotypes Associated with This Genotype

Genotype
MGI:5532305

ht2

• Allelic Composition: Kmt2b^tm1Afst/Kmt2b⁺
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased insulin secretion ( J:203736 )

• in response to glucose challenge

increased circulating glucose level ( J:203736 )

• in fasted mice and during intraperitoneal glucose tolerance test

increased circulating insulin level ( J:203736 )

• in fasted mice

impaired glucose tolerance ( J:203736 )

insulin resistance ( J:203736 )

adipose tissue

increased epididymal fat pad weight ( J:203736 )

liver/biliary system

liver/biliary system phenotype ( J:203736 )

N • mice exhibit normal liver weight

endocrine/exocrine glands

decreased insulin secretion ( J:203736 )

• in response to glucose challenge