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Phenotypes Associated with This Genotype
Genotype
MGI:5538390
cx1
Allelic
Composition
Ildr1Gt(D178D03)Wrst/Ildr1Gt(D178D03)Wrst
Tg(Cck-EGFP)BJ203Gsat/0
Genetic
Background
involves: 129S2/SvPas * C57BL/6J * FVB/NTac * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ildr1Gt(D178D03)Wrst mutation (1 available); any Ildr1 mutation (37 available)
Tg(Cck-EGFP)BJ203Gsat mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
digestive/alimentary system
• administration of HDL and C12 fails to induce increased intracellular calcium concentration in intestinal cells unlike wild-type mice
• however, intestinal cells respond normally to L-phenylalanine

homeostasis/metabolism
• following administration of C12 and chylomicrons fail to exhibit an increase in serum cholecystokinin (CCK) unlike wild-type mice
• however, administration of C12 and LDL or C12 and HDL induces increased serum CCK


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory