Phenotypes Associated with This Genotype

Genotype
MGI:5547986

ht2

• Allelic Composition: Nacc1^tm1.1Jlwa/Nacc1⁺
• Genetic Background: involves: 129S1/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal vertebrae morphology ( J:203277 )

• some mice exhibit an intermediate phenotype with T13/L5 configuration compared with wild-type mice

lumbar vertebral transformation ( J:203277 )

• some mice exhibit asymmetrical partial transformation of L6 into a sacral identity

decreased presacral vertebrae number ( J:203277 )

• in some E15 and adult mice

abnormal chondrocyte physiology ( J:203277 )

• reduced migration

• however, proliferation is normal