Phenotypes Associated with This Genotype

Genotype
MGI:5548178

cx5

• Allelic Composition: Pdgfa^tm2Cbet/Pdgfa^tm2Cbet; Pdgfc^tm1Nagy/Pdgfc^tm1Nagy
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

spina bifida ( J:205009 )

• in all mice

spina bifida occulta ( J:205009 )

• in some mice

digestive/alimentary system

abnormal small intestine morphology ( J:205009 )

• reduced thickness of the submucosal mesenchyme in the upper small intestine

decreased small intestinal villus number ( J:205009 )

• reduced number of villi in the upper small intestine

growth/size/body

decreased body size ( J:205009 )

skeleton

spina bifida occulta ( J:205009 )

• in some mice

kyphosis ( J:205009 )

• severe kyphosis of the thoracic spine in 3 of 11 mice

embryo

spina bifida ( J:205009 )

• in all mice

spina bifida occulta ( J:205009 )

• in some mice