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Phenotypes Associated with This Genotype
Genotype
MGI:5548180
cx3
Allelic
Composition		 Pdgfatm2Cbet/Pdgfatm2Cbet
Pdgfctm1Nagy/Pdgfctm1Nagy
Genetic
Background		 B6.129-Pdgfctm1Nagy Pdgfatm2Cbet
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdgfatm2Cbet mutation (1 available); any Pdgfa mutation (20 available)
Pdgfctm1Nagy mutation (0 available); any Pdgfc mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
spina bifida ( J:205009 )
• in all mice, but heterogeneity in severity
spina bifida occulta ( J:205009 )
• in 2 of 5 mice

nervous system
spina bifida ( J:205009 )
• in all mice, but heterogeneity in severity
spina bifida occulta ( J:205009 )
• in 2 of 5 mice

skeleton
spina bifida occulta ( J:205009 )
• in 2 of 5 mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory