Phenotypes Associated with This Genotype

Genotype
MGI:5550272

cn1

• Allelic Composition: Ndfip1^tm1.1Pmo/Ndfip1^tm1.1Pmo; Tg(Cd4-cre)1Cwi/0
• Genetic Background: involves: C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

esophageal inflammation ( J:205692 )

• eosinophilic inflammation

increased eosinophil cell number ( J:205692 )

• in the esophagus, small bowel and lung and to a lesser extent in the skin

increased activated T cell number ( J:205692 )

• in the spleen

skin inflammation ( J:205692 )

• later with lesser eosinophil infiltration than in Ndfip1^{Gt(RRD002)Byg} homozygotes

digestive/alimentary system

esophageal inflammation ( J:205692 )

• eosinophilic inflammation

integument

skin inflammation ( J:205692 )

• later with lesser eosinophil infiltration than in Ndfip1^{Gt(RRD002)Byg} homozygotes

hematopoietic system

increased eosinophil cell number ( J:205692 )

• in the esophagus, small bowel and lung and to a lesser extent in the skin

increased activated T cell number ( J:205692 )

• in the spleen