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Phenotypes Associated with This Genotype
Genotype
MGI:5550563
cx1
Allelic
Composition		 Glra2tm1.2Lngu/Y
Tg(mI56i-cre,EGFP)1Kc/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J * FVB/N * MF1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Glra2tm1.2Lngu mutation (0 available); any Glra2 mutation (9 available)
Tg(mI56i-cre,EGFP)1Kc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuronal migration ( J:202763 )
• fewer GFP+ cortical interneurons migrating into the cortical wall at E15.5
• however, only neurons traveling in the subventricular zone migratory stream
abnormal embryonic/fetal subventricular zone morphology ( J:202763 )
• fewer GFP+ cortical interneurons migrating into the cortical wall at E15.5
• however, only neurons traveling in the subventricular zone migratory stream

cellular
abnormal neuronal migration ( J:202763 )
• fewer GFP+ cortical interneurons migrating into the cortical wall at E15.5
• however, only neurons traveling in the subventricular zone migratory stream

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory