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Phenotypes Associated with This Genotype
Genotype
MGI:5559056
Allelic
Composition		 Cdkn2atm4Rdp/Cdkn2atm4Rdp
Krastm4Tyj/Kras+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn2atm4Rdp mutation (0 available); any Cdkn2a mutation (67 available)
Krastm4Tyj mutation (9 available); any Kras mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased sarcoma incidence ( J:125101 )
• mice injected intramuscularly with an adenovirus expressing Cre recombinase into the extremities or into the uterus develop soft tissue sarcomas

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
sarcoma DOID:1115 J:125101

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory