nervous system
• develop progressive amyloid deposition in cerebral cortices at around 9-12 months of age
• young (4 month) mutants treated with the anti-amyloid beta antibody 266 exhibit increased levels of monomer amyloid beta species in an antibody-bound form, without affecting that of total amyloid beta
|
homeostasis/metabolism
• develop progressive amyloid deposition in cerebral cortices at around 9-12 months of age
• young (4 month) mutants treated with the anti-amyloid beta antibody 266 exhibit increased levels of monomer amyloid beta species in an antibody-bound form, without affecting that of total amyloid beta
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
Alzheimer's disease | DOID:10652 | J:204270 |