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Phenotypes Associated with This Genotype
Genotype
MGI:5559506
cx7
Allelic
Composition		 Kdf1shd/Kdf1shd
Trp63tm2Brd/Trp63+
Genetic
Background		 involves: 129S7/SvEvBrd * C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdf1shd mutation (0 available); any Kdf1 mutation (17 available)
Trp63tm2Brd mutation (1 available); any Trp63 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
integument phenotype ( J:203995 )
N
• epidermal barrier formation, increased basal keratinocyte proliferation, lateral epidermis thickness and impaired keratinocyte differentiation defects observed in 1810019J16Rikshd homozygotes are rescued

limbs/digits/tail
limbs/digits/tail phenotype ( J:203995 )
N
• limb protrusion defects and tail-hindlimb fusion observed in 1810019J16Rikshd homozygotes homozygotes is rescued

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory