Phenotypes Associated with This Genotype

Genotype
MGI:5560502

hm1

• Allelic Composition: Bmpr2^b2b2556Clo/Bmpr2^b2b2556Clo
• Genetic Background: C57BL/6J-Bmpr2^b2b2556Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2556-004-1 (E16.5) exhibits parallel outflow tracts and ventricles appear thin which is diagnosed as PTA (Type A4) and ventricular non-copmaction by EFIC imaging and the heart is malrotated further to the left

cardiovascular system

abnormal myocardium compact layer morphology ( J:175213 )

• ventricular non-compaction

persistent truncus arteriosus type i ( J:175213 )

persistent truncus arteriosus type iv ( J:175213 )

• Type A4

atrioventricular septal defect ( J:175213 )

muscular ventricular septal defect ( J:175213 )

abnormal semilunar valve morphology ( J:175213 )

• absent semilunar valves

renal/urinary system

hydronephrosis ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )

• ventricular non-compaction