Phenotypes Associated with This Genotype

Genotype
MGI:5561310

• Allelic Composition: Trappc10^b2b2416Clo/Trappc10^b2b2416Clo
• Genetic Background: Trappc10^b2b2416Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2416-004-NB shows a hypoplastic thymus and thickened ventricular walls which is diagnosed as biventricular hypertrophy by EFIC imaging

cardiovascular system

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

atrioventricular septal defect ( J:175213 )

ventricular septal defect ( J:175213 )

nervous system

holoprosencephaly ( J:175213 )

anencephaly ( J:175213 )

vision/eye

anophthalmia ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

muscle

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

growth/size/body

heart left ventricle hypertrophy ( J:175213 )

heart right ventricle hypertrophy ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
agnathia-otocephaly complex		DOID:0060341	OMIM:202650	J:175213