Phenotypes Associated with This Genotype

Genotype
MGI:5561312

• Allelic Composition: b2b2459Clo/b2b2459Clo
• Genetic Background: C57BL/6J-b2b2459Clo

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mutant 2459-006-1 (E16.5) exhibits malalignment of the great arteries, shown to be double outlet right ventricle (DORV) by EFIC imaging

cardiovascular system

abnormal myocardium compact layer morphology ( J:175213 )

• Excessive myocardial trabeculation or noncompaction

double outlet right ventricle ( J:175213 )

double outlet right ventricle with atrioventricular septal defect ( J:175213 )

atrioventricular septal defect ( J:175213 )

ventricular septal defect ( J:175213 )

renal/urinary system

kidney cyst ( J:175213 )

muscle

abnormal myocardium compact layer morphology ( J:175213 )

• Excessive myocardial trabeculation or noncompaction

growth/size/body

kidney cyst ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cystic kidney disease		DOID:2975		J:175213